Publications
RELATIONSHIP BETWEEN GALECTIN-3 AND ASYMMETRIC DİMETHYLARINE IN DIALYSIS PATIENTS
Mar 11, 2025Journal TURKISH JOURNAL OF BIOCHEMISTRY
Publisher Annals of Clinical and Analytical Medicine
DOI 10.13140/RG.2.2.14693.72167
Issue 1
Volume 49
Asymmetric dimethylarginine (ADMA) is an inhibitor of the endogenous nitric oxide synthase. ADMA exits cells into the bloodstream via the cationic amino acid transporter family and is either excreted by the kidneys or eliminated in the liver. Galectin-3 (Gal-3) is a type of protein found in many different cell types in the body. It is expressed on the cell surface and then secreted into biological fluids. The purpose of the study was to evaluate Gal-3 and ADMA levels pre- and post-dialysis and determine the relationship between them. A significant difference was found in ADMA levels pre- and post-dialysis (P = 0.000). No significant difference was found in Gal-3 levels pre- and post-dialysis (P = 0.062). Although there is no relationship between ADMA and Gal-3 levels in the serum of kidney patients pre- and post-dialysis , the difference between ADMA levels could be considered as a biomarker that predicts the early assessment and progression of clinical kidney damage.
Rare case of hand bony involvement of sarcoidosis in a palestinian woman: A case report
Mar 20, 2024Journal Annals of Clinical and Analytical Medicine
Publisher Annals of Clinical and Analytical Medicine
DOI 10.4328/ACAM.22064
Issue Published Online: 2024-02-02
Sarcoidosis is a multisystem inflammatory illness with no recognised cause. Non-caseating granulomas are a characteristic of this illness. Bilateral hilar lymphadenopathy and lung infiltration are the most typical presentations. However, the disease is quite diverse and has an unexpected clinical outcome. Less often, there is bone involvement but considered serious and significant. Involvement of the bone is present in 1–15% of sarcoidosis patients. Hand involvement in sarcoidosis is uncommon and Sarcoid lesions of the hand occur in only around 0.2 percent of cases. We describe a case of sarcoidosis in Palestine with a history of finger swelling, radiographic and magnetic resonance imaging (MRI) findings showed bony involvement for increasing the awareness of the medical team and population.