Comparison between apolipoproteins (A4, B, C3, E) in the ratio and effecting on lipid profile of type 2 diabetic patients in Kirkuk city, Iraq

May 6, 2023 - May 7, 2023

Publisher مجلة كلية المصطفى الجامعة

DOI 3097-2522ISSN الرقم الدولي

Country iraq

Location Baghdad

Background: , is essential in the rising of cardiovascular (CV) risk. Lipids and glucose (T2DM)play a crucial role in energy metabolism. It is well known that patients with which characterized by increased in the lipid , diabetes often have dyslipidemiaHDL. The paper aims to investigate serum apolipoproteins and their except profiles effect on lipid profile of T2DM in a Kirkuk population. control study was conducted for patients with - based cases-The hospitalMethods: Type 2 diabetes patients that attended of the Diabetic center in K1 Hospital and Consultation Clinic of Kirkuk, and Azadi Teaching Hospital in Kirkuk during the August 2021 were screened for serum concentration of – period from March 2021lipids, lipoproteins especially in relation to , III, and apoE-IV, apoB, apoC-apoA(Exercise or physical activity, BMI, anthropometric measures (weight and height) 2 diabetes with high lipid were cases and Type from all patients were recorded. those without were controls. Among the Type 2 diabetes patients recruited for this study, serum lipid Results: significantly profile (total cholesterol, TG, LDL, VLDL) in T2DM patients was subjects, p < .001, while for HDL was not significantly higher than in control ± 139.44A4 of control (-The mean of APOdifferent from control group, p = .921. in %) 59.32± 70.12T2DM (< .001, was significantly larger than p %), 63.75A4 on lipid profile -APOefficiency of that indicate correlation to the level of lipid and small amount including cholesterol and triglyceride in most of control groups ) was significantly 33.55± 142.49APO_B mean for T2DM (T2DM patients. of lipoprotein, Which is < .001, from bad p ), 7.70± 95.57larger than for control (elevated in most of diabetic patients associated with elevated LDL level and total cholesterol indication the bad effect on lipoproteins. The findings of this study strengthen the fact that apoA4 is most Conclusion: rotien that play a major rule in maintain the level of cholesterol effective apolipopand triglyceride containing lipoprotein in normal state.

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