Publications
Respiratory Syncytial Virus (RSV) Companionship with Rhinovirus (RV)in Children with Respiratory Tract Infection(RTV) under Five years.
Nov 23, 2024Journal Malaysian Journal of Microbiology
Publisher Elaph madallah shweikh
DOI http://dx.doi.org/10.21161/mjm.240031
Issue 2024, pp. 218-221
Volume Vol 20(6)
Aims: Co-infections of rhinovirus and respiratory syncytial virus (RSV) are more common or severe infection, so this study aims to determine co-infection of respiratory tract infection (RTI). Methodology and results: 300 male and female children under five, who visited the Emergency Department of Pediatrics at Beiji Hospital, were the subject of a cross-sectional study. The study covered the period from October 2021 to the end of June 2022. An enzyme-linked immunosorbent test (ELISA) was used to detect the presence of antibodies to the human respiratory syncytial virus (HRSV) and human rhinovirus (HRV) in a serum sample. A single RSV and a single RV infection were found in 33(11%) and 39(13%). However, 87(29%) RSV co-infections were with RV infections. Children under one year were more susceptible to co-infection (58%). The proportion of females (62.06%) was a higher co-infection rate than males. Children with RSV co-infection with RV were more likely to experience fever (77.11%) and bronchiolitis (73.56%). Conclusion, significance and impact of study: It was concluded that both RSV and RV are common in children under the age of five, that when the two viruses coexist, each causes clinical symptoms, that children under one year are most vulnerable to co-infection, and that the age distribution of cases indicates the need for RSV and RV vaccines that can protect children early in life. Keywords: Co-infection, ELISA, respiratory syncytial virus, respiratory tract infection, rhinovirus
Serological Diagnosis of Respiratory Syncytial Virus by ELISA Technique among Children with Respiratory Tract Infections in Beiji City, Iraq
Feb 20, 2022Journal Tikrit Journal of Pure Science
Publisher Elaph madallah shweikh
DOI 10.25130/tjps.v28i1.1258
Volume 28(1)2023
T he study have been done to detect Human Respiratory syncytial virus (HRSV) infections among hospitalized children under 5 years old in Beiji city Salah-Aldin Governorate, in addition to identify the risk factors associated with the virus. Whole blood samples were taken from 300 hospitalized children between the end of October 2021, to the end of June 2022, each sample was analyzed for HRSV by immunoglobulin M (IgM) specific to HRSV determining from blood specimens in serum using enzyme-linked immune sorbent assay (ELISA) technique. Of the 300 serum samples, Respiratory syncytial virus (RSV) was found in 120 (40%), 63 (42%) females, and 57 (38%) males. The age group was more susceptible to infection between 7-12 months for RSV at a rate of 25%. The study revealed that 61.66% of children exposed to smoke from one or both parents was positive for RSV, while 38.33% showed negative results for the presence of RSV. Considering the type of feeding, the current study showed that RSV infection was demonstrated in a higher percentage in patients with bottle feeding 60%, while a low percentage was demonstrated in patients with breastfeeding at 13.3%. Our results indicated the prevalence of RSV among children after imposing vaccination and reducing nonpharmaceutical interventions