Wissam Mohammed Rashed
Research Interests
| Gender | MALE |
|---|---|
| Place of Work | Hawija Technical Institute |
| Position | Head of department |
| Qualification | Ph.d |
| Speciality | Chemistry |
| drwisam_hwj@ntu.edu.iq | |
| Phone | 07806071592 |
| Address | hiwija, kirkuk, Mosul, Iraq |
Publications
SYNTHESIS OF SOME NEW THIAZOLIDINONE COMPOUNDS DERIVED FROM SCHIFF BASES COMPOUNDS AND EVALUATION OF THEIR LASER AND BIOLOGICAL EFFICACY
Apr 3, 2025Journal Ann Trop & Public Health
DOI http://doi.org/10.36295/ASRO.2020.23728
Issue 7
Volume 23
In this work 6-fuloro-2-aminobenzothazol compound (R1) have been prepared from the reaction of aniline with appropriate potassium thiocyanate in presence cooled glacial acetic acid in such a way to temperature not exceeded above room temperature, Solution of 1.6ml of bromine in 6ml of glacial acetic acid, the reaction 6-fuloro-2-aminobenzothazol of with Hydrazine hydrate 6-fluoro-2-hydrazineylbenzo thiazole yielded compounds (R2). The research included synthesis of schiff base from the reaction of with appropriate aromatic aldehydes in presence of glacial acetic acidyieldeds compounds (R3-R7) 2-(2- benzylidenehydrazineyl)-6-chlorobenzo thiazole, and synthesis of thiazolidinone from the reaction of thioglycolic acid with schiff base,yieldeds compounds (R8-R12) chloro-N-(5-phenyl-2,5-dihydro-tetrazol-1- yl) benzo thiazol-2. The prepared compounds have been characterized by melting points and some physical properties besides the FT-IR, H-NMR spectra and quantitative analysis of elements (C.H.N.). The purity for these compounds was checked by TLC. The study is showed biological activity for chemical compounds, at three concentrations (10-2,10-3,10-4) mg/ml The minimum inhibitory concentration [MIC] have been determined with the reference of stander drugs the results showed that the thiazolidinone derivatives are better than growth of both types of bacteria gram-positive and gram–negative compared to drug, and evaluation of laser efficacy.
N-alkylation of substituted 2-amino benzothiazoles by 1,4-bis (bromo methyl) benzene on mixed oxides at room temperature and study their biological activity
Nov 8, 2022Journal Cite as: AIP Conference Proceedings
publisher Wissam Mohammed Al-Joboury, Khalid Abdulaziz Al-Badrany and Nabeel Jamal Asli
DOI http://doi.org/https://doi.org/10.1063/5.012346310.36295/ASRO.2020.23728
bstract. In this work, substituted 2-amino benzothiazoles (W1-4 ) were synthesized from, the reaction of aniline substituted with potassium thiocyanate in presence of broomin. The selective liquid phase N-alkylation of substituted 2- amino benzothiazoles by1,4-bis (Bromo methyl) benzene using Al2O3–OK as a catalyst in the presence of acetonitrile at room temperature (30 C) is described. synthesis of Al2O3–OK catalyst from the reaction of potassium nitrate with aluminum (III) oxide yielded compounds(W5 -8 ) .All these synthesized compounds were characterized on the basis of their by (IR and 1H-NMR, 13C-NMR, CHN, TLC) and physical methods, the study is showed biological activity for chemical compound, at three concentrations( 0.01,0.001,0.0001) mg/ml The minimum inhibitory concentration [MIC] have been determined with the reference of stander drugs. The rest of the substituted 2-amino benzothiazole derivatives showed moderate to good antibacterial activity, whereas the N-alkylation derivatives showed mild to low antibacterial activity. Thus, it is concluded from the screening results that benzothiazole derivatives were most effective against all microorganisms at a concentration of 50 mg/mL compared to drug.
Synthesis and characterization of some azetidine Derivatives that derived from 6-Bromo-4-Fluoro-2-Aminobenzothiazole and Study Their biological …
Feb 1, 2022Journal Journal of Education and Scientific Studies
publisher A Khalid, Amena Alyas Ahmed, MR Wissam
Volume 23
the reaction between 4-Bromo-2-fluoro aniline with potassium thiocyanate in presence of liquid brome. Synthesis of Schiff base from reaction 6-Bromo-4-fluoro-2-aminobenzothiazole (w2-W5). The reaction of chloroactyl chloride with Schiff base yielded compounds (w6-9) azetidine. All the new compounds have been characterized using infrared spectroscopy (IR), proton nuclear magnetic resonance (H1-NMR) and physical methods. The antibacterial activity has beentested in vitro by the disk diffusion assay method against two kinds of bacteria gram positiveand gram negative. The minimum inhibitory concentration [MIC] have been determined withthe reference of stander drugs, the results showed that the azetidine derivatives are betterthan growth of both types of bacteria (gram-positive and germ–negative compared to drug
Synthesis of new azo dye compounds derived from 2-aminobenzothiazole and study their biological activity
Jun 16, 2021Journal Materials Today: Proceedings
publisher Wissam Mohammed Al-Joboury, Khalid Abdulaziz Al-Badrany and Nabeel Jamal Asli
Volume 47
In this work, new 2-amino benzothiazole (W1) were synthesized from the reaction between aniline substituted with potassium thiocyanate in presence of broom. (W1) reaction with phenol substituted to give azo dyes compound (W2-W5). Polyacrylic acid was converted into poly acryloyl chloride by reaction poly acrylic acid with thionyl chloride was dissolved in acetonitrile with reaction different organic compounds. (W1-9) characterized were using (IR) and (HNMR-CNMR-CHN–TLC) techniques and the analysis revealed biological activity for chemical compounds at three concentrations (0.01, 0.001, 0.0001) mg/ml. (MIC) was calculated using standard drugs as a comparison. The findings revealed that azo derivatives outperformed medication in inhibiting the growth of gram negative & positive bacteria.
Synthesis and evaluation of the biological activity of some new pyrimidin derivatives derived from pyrazolin
Jan 3, 2021Journal Eurasian Chemico-Technological Journa
publisher A Khalid, Amena Alyas Ahmed, MR Wissam
Issue 3
Volume 21
In this work, pyrazoline was prepared from reaction ethyl acetoacetate with hydrazine hydrate. Chalcone (α, β-unsaturated compounds)(A1-3) have been prepared from the reaction of appropriate aromatic aldehydes derivatives with pyrazoline (ketone) with glacial acetic acid. The pyrimidin derivatives (A4-9) was obtained by two ways first from reaction Chalcones (A1-3) with thiourea in presence of 10% NaOH, second from reaction Chalcones (A1-3) with cyanogoanidine in presence of 10% NaOH. All these synthesized compounds were characterized by some physical properties such as the color and melting point and and spectrophmatic methods using (IR, 13C-NMR and 1H-NMR). The study is showed biological activity for chemical compounds, at three concentration 0.01, 0.001, 0.0001) mg/ml The minimum inhibitory concentration [MIC] have been determined with the reference of stander drugs the results …
ynthesis of Some New pyrazoline Compounds Derived from chalcones Compounds and Study Their biological activity
Sep 1, 2018Journal journal of kerbala university
publisher A Khalid, Amena Alyas Ahmed, MR Wissam
Issue 3
Volume 14
In this work, α-β-unsaturated compounds (w1-9) have been prepared from the reaction of acetophenone derivatives with appropriate aromatic aldehydes in presence of NaOH (10%), The research included synthesis of pyrazoline from the reaction of semicrbazid with chalcones yieldedscompounds (W10-18) 3.3-di-p. toly-4, 5dihydro-1Hpyrazole-1-Carboxamide). All thesesy ntheized compounds were characterized on the basis of their (IRand H1NMR). The study is showed biological activity for chemical compounds, at three concentration 0.01, 0.001, 0.0001) mg/ml The minimum inhibitory concentration [MIC] have been determined with the reference of stander drugs the results showed that the pyrazoline derivatives are better than growth of both types of bacteria (gram-positive and garm–negative compared to drug.