بكالوريوس

Jan 9, 2010 - May 6, 2014

ماجستير

Jan 10, 2020 - Dec 12, 2023

Association of Protein Glycosylation Disorders with Human Diabetes Diseases

Feb 3, 2025

Journal International Journal of Medical and All Body Health Research

DOI https://www.researchgate.net/deref/https%3A%2F%2Fdoi.org%2F10.54660%2FIJMBHR.2025.6.2.143-1?_tp=eyJjb250ZXh0Ijp7ImZpcnN0UGFnZSI6Il9kaXJlY3QiLCJwYWdlIjoicHVibGljYXRpb24iLCJwcmV2aW91c1BhZ2UiOiJwcm9maWxlIiwicG9zaXRpb24iOiJwYWdlQ29udGVudCJ9fQ

Issue 2

Volume 6

Glycosylation is a vital post-translational modification crucial for protein function, folding, and stability. Disorders of protein glycosylation have significant implications for human diseases, including diabetes mellitus. This review explores the biological mechanisms underpinning protein glycosylation, types of glycosylation disorders, and their clinical manifestations, focusing on their association with diabetes. Recent studies demonstrate shared molecular pathways between glycosylation disorders and diabetes pathophysiology, emphasizing oxidative stress, inflammation, and impaired insulin signaling. Understanding these links offers prospects for novel diagnostic strategies and therapeutic interventions. Continuous research into the molecular crosstalk between glycosylation and glucose metabolism is essential for developing precision medicine approaches to manage diabetes and related complications.

Revolutionizing Infection Control: Harnessing MXene‐Based Nanostructures for Versatile Antimicrobial Strategies and Healthcare Advancementss

May 4, 2024

Journal Chemistry & Biodiversity

Issue 5

Volume 21

The escalating global health challenge posed by infections prompts the exploration of innovative solutions utilizing MXene‐based nanostructures. Societally, the need for effective antimicrobial strategies is crucial for public health, while scientifically, MXenes present promising properties for therapeutic applications, necessitating scalable production and comprehensive characterization techniques. Here we review the versatile physicochemical properties of MXene materials for combatting microbial threats and their various synthesis methods, including etching and top‐down or bottom‐up techniques. Crucial characterization techniques such as XRD, Raman spectroscopy, SEM/TEM, FTIR, XPS, and BET analysis provide insightful structural and functional attributes. The review highlights MXenes’ diverse antimicrobial mechanisms, spanning membrane

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Prevalence and distribution of Staphylococcus aureus virulence enzyme isolated from clinical and environmental sources

Jan 2, 2022

Journal South Asian Journal of Research in Microbiology

Issue 2

Volume 13

The goal of this study was to isolate and identify Staphylococcus aureus from clinical and environmental sources. This study also looked at the prevalence and distribution of different virulence enzymes among its isolates. For this objective, 65 samples were collected and dispersed among 50 distinct clinical samples and 15 environmental (soil, water, and air) samples. The results revealed that 20 bacterial isolates were S. aureus. The isolation rate was 30.76% from all samples, with 13 isolates 20% from a clinical source and 7 isolates 10.76% from an environmental source. The phenotypic detection of virulence enzymes revealed that all isolates, including environmental isolates, produced virulence enzymes (between two and six enzymes), indicating the clinical importance. The isolates produced virulence enzymes at different rates. The results revealed a clear rise in the rate of production of the enzymes: lecithinase and lipase producing at a rate of 95%, protease at 90%, urease at 80%, hemolysin at 60%, and

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Inhibition of virulence enzymes of Staphylococcus aureus using essential oils and alcoholic extracts of some plants

Dec 12, 0024

Journal Malaysian Journal of Microbiology

Issue 6

Volume 20

Staphylococcus aureus is an opportunistic pathogen that causes many threatening diseases, and its severity is linked to its possession of virulence factors that help it colonize and promote bacterial infection. This study looked into the possibilities of suppressing virulence enzymes in S. aureus employing essential oils and alcoholic extracts of cinnamon, ginger, peppermint, pomegranate peels and grape seeds. The studied virulence enzymes included beta-lactamase, hemolysin, urease, lecithinase, lipase and protease. Methodology and results: According to the results, the MIC values of the essential oils ranged from 100-300 µL/mL. The MIC values for the alcoholic extracts examined ranged from 125-300 mg/mL. Cinnamon oil inhibited both lecithinase and lipase. Its alcoholic extract inhibited the hemolysin and beta-lactamase. The alcoholic extract of ginger inhibited hemolysin and lipase. Peppermint extract

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