Publications
A short review about chronic myeloid leukemia
Jan 9, 2023Journal ournal of Life and Bio-sciences Research
Issue 1
Volume 4
Chronic myeloid leukemia (CML) develops as a result of a clonal process in a pluripotent stem cell. Anemia, granulocytosis, basophilia,thrombocytosis and splenomegaly are some of the symptoms of the condition. According to clinical findings, the illness progresses through three stages, each of which is identified by a rise in number of the blast cells in peripheral blood or bone marrow: chronic(10%), accelerated (10-19%) and acute leukemia-like blast crisis (20%). Most CML cases could be preliminary diagnosed by the presence of splenomegaly in addition to mutation in the BCR-ABL gene as well as complete blood count (CBC) test. Moreover, a bone marrow biopsy can provide a major confirmation of the disease process and staging. Definitive diagnosis of the disease can be either achieved through fluorescence in situ hybridization (FISH) or polymerase chain reaction PCR technique.
Detection of Antibiotic Resistance Genes (CTX-M, Van A and Van B) of Enterococcus faecalis Isolated from Children with Bacteremia by RT-PCR
Jan 1, 2023Journal Archives of Razi Institute
DOI 10.22092/ARI.2022.359148.2380
Issue 1
Volume 78
Fever is one of the most common diseases affecting humans, as it results from any disease or development and worsening of the disease for most people with widespread infections in the body. Therefore, this study aimed to evaluate antibiotic resistance genes (CTX-M, Van A and Van B) of Enterococcus faecalis isolated from children with bacteremia by RT-PCR. A total of 200 children was enrolled in the study, 100 children with fever and 100 healthy children (not suffering from any problem); that is, they are a control group for the detection of antibiotic resistance genes (CTX-M, Van A and Van B) of Enterococcus faecalis by RT-PCR.
Modes of Transmission and Virulence Factors of Staphylococcus Aureus (Review)
Nov 10, 2022Journal Himalayan Journal of Applied Medical Sciences and Research
DOI 10.47310/hjamsr.2022.v03i02.040
Issue 6
Volume 3
taphylococcus aureus is a pathogen which colonizes the epidermisand nasal passages of the anterior slits, the alimentary canal, the genitourinarytract, and the pharynx. There are numerous ailments that this bacterium can cause, from mild infections of the skin to fatal pneumonia and sepsis. Bacteria from S. aureus can pass easily through one genus to another. The transition from humans to animals. S. aureus infections are zoonotic. It can be spread from animal to person by bites, scratches, working with diseased animal body parts or bones, and skin sores developed during contact with sick or carrier animals. The treatment of infections that caused by S. aureus is complicated by resistance of the antibiotic, and there is no effective vaccination. The incredibly high number of toxins as well as other virulence factors produced by S. aureus, as well as their impact on disease, have sparked ongoing and growing interest.