Optometry Techniques Department Students

Year: 2025

Academic Degree: Diploma

Supervisor Type: Supervisor

Supervisor State: Ungraduated

Optometry Techniques Department Students Level Two, at Al-Huwaija Technical Institute. I

Master

Sep 28, 2019 - Nov 6, 2022

a Master's degree in Life Sciences

Bachelor's

Oct 1, 2015 - Jun 20, 2019

College of Science / Department of Life Sciences / University of Kirkuk

Evaluation of the hepatoprotective role of ethanolic Saussurea lappa root extract in female rats experimentally exposed to propylthiouracil

Jan 29, 2023

Journal Tikrit Journal of Pure Science

publisher Tikrit Journal of Pure Science

DOI 10.4308/hjb.30.6.1054-1060

Issue 6

Volume 27

Propylthiouracil (PTU) is often used to produce experimental hypothyroidism. In general, PTU generates hepatotoxicity, albeit with dissimilar incidence rates of hepatotoxicity. This study examined the hepatoprotective effects of Saussurea lappa root ethanol extract on experimentally induced hepatotoxicity in female rats. For this study, 25 adult female albino rats were placed into five equal groups: control, PTU, post treated with S. lappa extract, co-administered PTU with S. lappa extract 300mg/kg, and post-treated with levothyroxine. Serum gamma-glutamyl transferase (GGT) activity, total protein, thyroid hormones (T3, T4, and TSH), and oxidative stress parameters (catalase, superoxide dismutase, reduced glutathione, and lipid peroxidation levels) were measured. The liver tissue underwent histological examination. Current findings revealed that S.lappa ethanol root extract significantly improved hepatotoxicity as evidenced by reversal of various biochemical and histopathological changes in female rats. Current study has shown that this promising impact may be due to the antioxidant and free radical scavenging characteristics of S.lappa constituents.

Read Publication

Cardioprotective Activity of Costus Root Ethanol Extract in Experimentally-Induced Hypothyroidism in Female Albino Rats

Jul 3, 2023

Journal HAYATI Journal of Biosciences

publisher IPB University

DOI 10.4308/hjb.30.6.1054-1060

Issue 30

Volume 6

Hypothyroidism is a popular endocrine disorder caused by a thyroid hormone deficit. Changes in the state of the thyroid gland significantly affect many organs, including the heart. This study examined the cardioprotective effects of an artificially induced hypothyroidism in female rats using an ethanol extract from the root plant Saussurea lappa (Costus). For the current study, 25 adult female albino rats were employed. They were split into five equal groups, including control, hypothyroid group, post-treatment group with costus extract, co-administered hypothyroid group with costus extract, and post-treatment group with levothyroxine. Thyroid hormones (T3, T4, and TSH), lipid profile, and oxidative stress indicators (catalase, superoxide dismutase, reduced glutathione, and lipid peroxidation levels) were also measured in the serum. The heart muscle was the subject of a histological research. The findings suggested that Costus root ethanol extract improved hypothyroidism in female rats, as proven by the reversal of many biochemical abnormalities and improvements in the heart's histology. Our study indicates that the root of Costus exhibited cardioprotection efficiency against hypothyroidism-induced serious effects on the heart, The antioxidant and radical-scavenging properties of its components may be responsible for this promising effect.

Read Publication